Identifying key genes involved in human brain development provides novel insights into biological processes underlying the evolution of the human neocortex and the treatment of brain diseases. During prenatal brain development, ion channels are ubiquitous across several cell types, including progenitor cells and migrating neurons, but their function has been unclear. In this webinar brought to you by 10x Genomics, Richard Smith discusses how his team used single cell approaches to identify the contributions of ion-conducting proteins to human cerebral cortex development. These genetic studies and recent in utero animal modeling work suggest that precise control of ionic flux contributes to in utero developmental processes such as neural proliferation, migration, and differentiation.
Topics to be covered
How single cell approaches help researchers characterize human cerebral cortex development
The role of ionic flux in in utero developmental processes
The functional role for a sodium channel subtype and a sodium/potassium ATPase pump in human neocortical folding
Tuesday, May 18, 2021
12:00 - 1:00 PM Eastern Time
Meet the speaker
Richard Smith, PhD Instructor Division of Genetics and Genomics Boston Children’s Hospital Harvard Medical School
TS_Webinar_Gaining Biological Insights into Brain Development Using Single Cell Technologies May 18, 2021
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