--- title: Characterizing Proteolysis During SARS-CoV-2 Infection description: Identifying cellular targets and cleaved products of proteases during SARS-CoV-2 infection. image: https://webinars.the-scientist.com/hubfs/560x292-Nov-02-2021-05-10-34-84-PM.jpg --- ![990x120](https://webinars.the-scientist.com/hs-fs/hubfs/TS%20Webinars/Thermo%20December%208th,%202021/990x120.jpg?width=990&name=990x120.jpg "990x120") # Event Overview Viral and host cell proteases play an important role in SARS-CoV-2 infection and replication. Viral proteases cleave cellular proteins to divert the host protein synthesis machinery to make viral proteins. Additionally, viral entry requires S protein cleavage by cellular proteases. Using mass spectrometry, researchers identify new protein fragments generated after the proteolytic cleavage of viral and cellular proteins. In this webinar brought to you by Thermo Fisher Scientific, Edward Emmott will discuss the identification and importance of previously unknown cleavage sites in SARS-CoV-2 proteins, including S protein and nucleocapsid, and new protease substrates essential for efficient SARS-CoV-2 replication in cells. **Topics to be covered** Mass spectrometry approaches to study proteolytic cleavage during SARS-CoV-2 infection Functions of viral and cellular proteases during viral infection Multiplexing protein N-terminal sequencing workflows | ![](https://webinars.the-scientist.com/hs-fs/hubfs/Images/TS/Webinars/calendar%20icon.png?width=50&name=calendar%20icon.png) | **Wednesday, December 8, 2021** | | --- | --- | | ![](https://webinars.the-scientist.com/hs-fs/hubfs/Images/TS/Webinars/clock%20icon.png?width=50&name=clock%20icon.png) | **11:00 AM - 12:00 PM Eastern Time** | | --- | --- | Meet the speaker ![Manara.png](https://webinars.the-scientist.com/hubfs/TS%20Webinars/Thermo%20December%208th,%202021/Emmott%20Circle.png "Manara.png") Edward Emmott, PhD Tenure-Track Fellow Centre for Proteome Research Department of Biochemistry and Systems Biology University of Liverpool **Sponsored by** [![thermo](https://webinars.the-scientist.com/hs-fs/hubfs/1.1-%20All-Images/LM/Webinars/Sponsor%20logos/Thermo%20Fisher%20Scientific_logo_cmyk_ez.jpg?width=250&name=Thermo%20Fisher%20Scientific_logo_cmyk_ez.jpg "thermo")](https://www.thermofisher.com/ca/en/home.html) # Register ### TS\_WEBINAR\_Thermo Labtools\_December 8, 2021 You must have Javascript and Cookies enabled to access this webcast. Information you provide will be shared with the sponsors for this content. *The Scientist* or its sponsors may contact you to offer you content or products based on your interest in this topic. You may opt-out at any time. The Scientist c/o LabX Media Group 1000 N West Street, Suite 1200, Wilmington, Delaware, United States, 19801 Toll Free: 888.788.0328 | Phone: 705.528.6888 Email: [privacy@the-scientist.com](mailto:privacy@the-scientist.com) [Privacy Policy](https://www.the-scientist.com/privacy-policy) © 1986-2022 [The Scientist](http://the-scientist.com/)   [![The Scientist Logo\_white](https://webinars.the-scientist.com/hs-fs/hubfs/The%20Scientist%20Logo_white.png?width=702&name=The%20Scientist%20Logo_white.png "The Scientist Logo_white")](https://www.the-scientist.com) The Scientist needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our [Privacy Policy.](https://www.the-scientist.com/privacy-policy)