--- title: Multiomic Single-Cell Analysis Identifies a Unique Stem and Progenitor Population --- ![990x120 August 13](https://webinars.the-scientist.com/hs-fs/hubfs/990x120%20August%2013.png?width=990&name=990x120%20August%2013.png "990x120 August 13") # Event Overview Hematopoietic stem and progenitor cells (HSPCs) are capable of generating a large diversity of blood cells throughout the human lifespan. Although these cells have been extensively evaluated, there remains significant uncertainty in the degree of heterogeneity within HSPC subpopulations and their associated differentiation trajectories. Identifying HSPC phenotypic diversity is important for better understanding the pathogenesis of numerous blood disorders, including hematologic malignancies. In this webinar brought to you by *The Scientist* and BD Biosciences, Margaret Nakamoto will introduce the BD Rhapsody™ Single-Cell Analysis System with whole transcriptome analysis (WTA) and BD® AbSeq Antibody-oligo surface marker evaluation, including the data workflow ranging from sample preparation to cell type identification and expression analyses. Ravi Majeti will then discuss how he and his team used concurrent RNA and BD® AbSeq Antibody-oligo multiplexed surface marker analysis to improve HSPC clustering and characterize specific phenotypic states along unique hematopoietic differentiation trajectories. **Topics to be covered** - Application of single-cell multiomics to healthy bone marrow mononuclear cells (BMMCs) - Identification of cell type clusters and surface marker associations using combined single-cell whole transcriptome amplification and surface marker analysis - Correlation of cell types with both canonical and novel surface markers and how deconvolution analysis provides preliminary insights into their potential clinical relevance in acute myeloid leukemia (AML) | ![](https://webinars.the-scientist.com/hs-fs/hubfs/Images/TS/Webinars/calendar%20icon.png?width=50&name=calendar%20icon.png) | **Thursday, August 13, 2020** | | --- | --- |   | ![](https://webinars.the-scientist.com/hs-fs/hubfs/Images/TS/Webinars/clock%20icon.png?width=50&name=clock%20icon.png) | **2:30 - 4:00 PM, Eastern Standard Time** | | --- | --- | Speakers ![Nakamoto.png](https://webinars.the-scientist.com/hubfs/Nakamoto%20100.png "Nakamoto.png") Margaret Nakamoto, PhD Manager, Genomics BD Biosciences ![Majeti.png](https://webinars.the-scientist.com/hubfs/Majeti%20100.png "Majeti.png") Ravi Majeti, MD, PhD Professor of Medicine Chief, Division of Hematology Institute for Stem Cell Biology and Regenerative Medicine Stanford University School of Medicine ![BD.png](https://webinars.the-scientist.com/hs-fs/hubfs/BD%20logobox.png?width=200&name=BD%20logobox.png "BD.png") # Register Now ### Multiomic Single-Cell Analysis Identifies a Unique Stem and Progenitor Population You must have Javascript and Cookies enabled to access this webcast. Information you provide will be held in confidence and will be shared with the sponsoring vendor(s) of this webinar. We may use the information to contact you about your account and to let you know about related programs and products; you may opt-out at any time. This allows *The Scientist* to keep these webinars free of charge for our readers. The Scientist c/o LabX Media Group 1000 N West Street, Suite 1200, Wilmington, Delaware, United States, 19801 Toll Free: 888.788.0328 | Phone: 705.528.6888 Email: [privacy@the-scientist.com](mailto:privacy@the-scientist.com) [Privacy Policy](https://www.the-scientist.com/privacy-policy) © 1986-2022 [The Scientist](http://the-scientist.com/)   [![The Scientist Logo\_white](https://webinars.the-scientist.com/hs-fs/hubfs/The%20Scientist%20Logo_white.png?width=702&name=The%20Scientist%20Logo_white.png "The Scientist Logo_white")](https://www.the-scientist.com) The Scientist needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our [Privacy Policy.](https://www.the-scientist.com/privacy-policy)