--- title: Genetic and Spatial Heterogeneity in Human Papillomavirus-Associated Oropharyngeal Cancer --- ![990x120 sept 8 10x](https://webinars.the-scientist.com/hs-fs/hubfs/990x120%20sept%208%2010x.png?width=990&name=990x120%20sept%208%2010x.png "990x120 sept 8 10x") # Event Overview Head and neck cancers arising from the upper aerodigestive tract are the sixth leading cause of cancer-related mortality, with over 550,000 new cases per year. Though it continues to be prevalent, the etiology of oropharyngeal cancer (OPC; cancer of the tonsil and base of tongue) has completely changed in the last 30 years. Now, human papillomavirus (HPV) is the leading cause of OPC. While patients with viral OPC tend to be younger and have a superior response to treatment and better prognosis compared with non-viral-OPC patients, the biological differences between these cancers are not well understood due to the paucity of genomic data in the viral-OPC population. The underlying genetic drivers of diverse cancer cell phenotypes, or "tumoral heterogeneity,” affect clinical outcomes but have not been studied in detail. In this webinar hosted by *The Scientist* and sponsored by 10x Genomics, Joseph Powell will discuss how heterogeneous subpopulations of HPV+ head and neck cancer cells drive unique disease states, cell–cell interactions, and microenvironment dynamics, and have implications for cancer behavior, metastasis, and response to treatment. **Topics to be covered** - How tumoral heterogeneity in head and neck cancer affects clinical outcomes - How to study heterogeneous subpopulations of HPV+ cancer cells using single-cell and spatial techniques | ![](https://webinars.the-scientist.com/hs-fs/hubfs/Images/TS/Webinars/calendar%20icon.png?width=50&name=calendar%20icon.png) | **Tuesday, September 8, 2020** | | --- | --- |   | ![](https://webinars.the-scientist.com/hs-fs/hubfs/Images/TS/Webinars/clock%20icon.png?width=50&name=clock%20icon.png) | **5:00 - 6:00 PM, Eastern Standard Time** | | --- | --- | Speaker ![Powell.png](https://webinars.the-scientist.com/hubfs/Powell%20100.png "Powell.png") Joseph Powell, PhD Associate Professor Garvan Institute of Medical Research [![10x.png](https://webinars.the-scientist.com/hs-fs/hubfs/10x%20NEW%20NEW.png?width=200&name=10x%20NEW%20NEW.png "10x.png")](https://www.10xgenomics.com/) # Register Now ### Genetic and Spatial Heterogeneity in Human Papillomavirus-Associated Oropharyngeal Cancer You must have Javascript and Cookies enabled to access this webcast. Information you provide will be held in confidence and will be shared with the sponsoring vendor(s) of this webinar. We may use the information to contact you about your account and to let you know about related programs and products; you may opt-out at any time. This allows *The Scientist* to keep these webinars free of charge for our readers. The Scientist c/o LabX Media Group 1000 N West Street, Suite 1200, Wilmington, Delaware, United States, 19801 Toll Free: 888.788.0328 | Phone: 705.528.6888 Email: [privacy@the-scientist.com](mailto:privacy@the-scientist.com) [Privacy Policy](https://www.the-scientist.com/privacy-policy) © 1986-2022 [The Scientist](http://the-scientist.com/)   [![The Scientist Logo\_white](https://webinars.the-scientist.com/hs-fs/hubfs/The%20Scientist%20Logo_white.png?width=702&name=The%20Scientist%20Logo_white.png "The Scientist Logo_white")](https://www.the-scientist.com) The Scientist needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our [Privacy Policy.](https://www.the-scientist.com/privacy-policy)