Approximately 40% of human diseases may be attributable to defects in the cellular proteostasis machinery, including the ubiquitin-proteasome system. Accumulation of misfolded, damaged, or aggregated proteins can lead to prolonged stress, accumulation of reactive oxygen species, and cell death. In this webinar, brought to you by Bio-Techne, Jennifer Johnston will discuss how her research of ubiquitin-proteasome system elements, including Parkin E3 ligase, is used to diagnose and treat diseases caused by defects in proteostasis pathways.
Topics to be covered
The basics of the ubiquitin-proteasome system
The biology and druggability of ubiquitin E3 ligases
Modifications of ubiquitin proteins and their therapeutic and diagnostic applications
Wednesday, September 29, 2021
2:30 - 3:30 PM Eastern Time
Jennifer Johnston, PhD Cofounder and CEO NysnoBio
TS_WEBINAR_Bio-Techne_TSU_Pioneering Research in E3 Ubiquitin Ligase Biology and Applications to Drug Discovery Sept 29, 2021_IO#403836
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