--- title: Resolving Cell Subtype Specialization with scRNA and RNAscope --- ![Transcriptome-Scale Spatial \_990x120](https://webinars.the-scientist.com/hs-fs/hubfs/Transcriptome-Scale%20Spatial%20_990x120.png?width=990&name=Transcriptome-Scale%20Spatial%20_990x120.png "Transcriptome-Scale Spatial _990x120") [**![watch on demand (2)](https://webinars.the-scientist.com/hs-fs/hubfs/watch%20on%20demand%20(2).png?width=150&name=watch%20on%20demand%20(2).png)**](https://bit.ly/2I1g6pv) **If you have already registered, follow this link and click on "Already Registered?" to enter your email address and view the webinar.** [https://bit.ly/prefrontal-cortex-visium-spatial-10x](https://bit.ly/prefrontal-cortex-visium-spatial-10x) # Event Overview Differences in pathology and gene expression associated with neuropsychiatric disorders can be localized to specific layers in the human brain. Scientists from the Lieber Institute for Brain Development sought to define the laminar topography of gene expression in the human dorsolateral prefrontal cortex (DLPFC), a brain area implicated in a number of neuropsychiatric disorders, using the Visium Spatial Gene Expression Solution from 10x Genomics. In this webinar sponsored by 10x Genomics, Kristen Maynard and Leonardo Collado-Torres will describe How they mapped and measured total mRNA within the tissue context. How they integrated their data with various neuropsychiatric disorder gene sets to demonstrate preferential layer-specific expression of autism spectrum disorder (ASD) risk genes, exemplifying the potential of the data for clinical translation. How the researchers implemented the Visium Spatial Gene Expression Solution in human brain tissue for the first time. The importance of conducting such studies for neuroscience research and beyond. | ![](https://webinars.the-scientist.com/hs-fs/hubfs/Images/TS/Webinars/calendar%20icon.png?width=50&name=calendar%20icon.png) | **Thursday, March 19, 2020** | | --- | --- |   | ![](https://webinars.the-scientist.com/hs-fs/hubfs/Images/TS/Webinars/clock%20icon.png?width=50&name=clock%20icon.png) | **2:30 - 4:00 PM, Eastern Standard Time** | | --- | --- | Speakers ![Anderson.png](https://webinars.the-scientist.com/hubfs/Courtney_Anderson.jpg "Anderson.png") Courtney Anderson, PhD Senior Product Marketing Manager Spatial Solutions 10x Genomics ![Maynard.png](https://webinars.the-scientist.com/hubfs/maynard%20100.png "Maynard.png") Kristen Maynard, PhD Research Scientist Lieber Institute for Brain Development ![Collado.png](https://webinars.the-scientist.com/hubfs/collado%20100.png "Collado.png") Leonardo Collado-Torres, PhD Research Scientist Lieber Institute for Brain Development ![10x.png](https://webinars.the-scientist.com/hs-fs/hubfs/10x%20logobox.png?width=200&name=10x%20logobox.png "10x.png") # Register Now ### Transcriptome-Scale Spatial Gene Expression in the Human Dorsolateral Prefrontal Cortex You must have Javascript and Cookies enabled to access this webcast. Information you provide will be held in confidence and will be shared with the sponsoring vendor(s) of this webinar. We may use the information to contact you about your account and to let you know about related programs and products; you may opt-out at any time. This allows *The Scientist* to keep these webinars free of charge for our readers. The Scientist c/o LabX Media Group 1000 N West Street, Suite 1200, Wilmington, Delaware, United States, 19801 Toll Free: 888.788.0328 | Phone: 705.528.6888 Email: [privacy@the-scientist.com](mailto:privacy@the-scientist.com) [Privacy Policy](https://www.the-scientist.com/privacy-policy) © 1986-2022 [The Scientist](http://the-scientist.com/)   [![The Scientist Logo\_white](https://webinars.the-scientist.com/hs-fs/hubfs/The%20Scientist%20Logo_white.png?width=702&name=The%20Scientist%20Logo_white.png "The Scientist Logo_white")](https://www.the-scientist.com) The Scientist needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our [Privacy Policy.](https://www.the-scientist.com/privacy-policy)