CRISPR-Cas technology has radically changed how transgenic models are created. Through CRISPR approaches, researchers have pioneered how to create complex animal models, including long cassette knock-ins and conditional knockout mouse models. Techniques such as Easi (Efficient Additions with ssDNA Inserts)-CRISPR and GONAD (Genome editing via Oviductal Nucleic Acids Delivery) have become prevalent for animal transgenesis.
This Technique Talk will offer a historical overview of mouse transgenic technologies and discuss how CRISPR-Cas has redefined these traditional gold standards to give scientists more flexibility and capability than ever before.
Monday, August 30, 2021
2:30 - 3:30 PM Eastern Time
Instructor
Channabasavaiah B. Gurumurthy, MVSC, PhD Director, Mouse Genome Engineering Core Facility Professor of Pharmacology and Experimental Neuroscience University of Nebraska Medical Center
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TS_WEBINARSIGNUP_TSU_Technique Talk: Redefining Mouse Transgenesis with CRISPR-Cas Technology August 30, 2021_Multi
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